
AP Biology Practice Exam
1
Free-Response Section
Scoring Guidelines
Question 1: Interpreting and Evaluating Experimental Results 9 points
Learning Objectives: SYI-1.B.2
SYI-1.C1
IST-1.N.3
(A) Describe the three structural components of an RNA nucleotide monomer.
• An RNA nucleotide has the following three structural components:
a five-carbon sugar (ribose), a phosphate group, and a nitrogen base (adenine,
cytosine, guanine, or uracil).
1 point
Explain the role of RNA polymerase during transcription.
Accept one of the following:
• RNA polymerase synthesizes a new mRNA molecule based on a DNA template
by matching the current DNA base with the proper complement.
• RNA polymerase joins or bonds the newly paired RNA nucleotide and the
growing RNA strand with a covalent bond.
1 point
Total for part (A) 2 points
(B) Identify the dependent variable in the experiments.
• The maximum elongation rate of the mRNA
1 point
Identify a control group missing from the second experiment.
• An appropriate control group missing from the second experiment.
Either of the strains from the first experiment (wild strain or experimental
strain) but without amanitin is an appropriate control for the second
experiment, but there may be other appropriate controls.
1 point
Justify the need for this control group in the second experiment.
• The response correctly indicates why the missing control is needed to
correctly interpret the results of experiment 2. If either the wild strain or
experimental strain from experiment 1 is selected, then the justification
is that the effect of amanitin on the maximum elongation rate cannot be
determined without comparison to the maximum elongation rate under the
same conditions without amanitin.
1 point
Total for part (B) 3 points